iPTMnet Report for Q6PD74 (AAGAB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PD74 / AAGAB_HUMAN
Protein Name Alpha- and gamma-adaptin-binding protein p34
Gene Name Name: AAGAB
Organism Homo sapiens (Human)

PRO ID PR:Q6PD74
DAG View
PRO Name alpha- and gamma-adaptin-binding protein p34 (human)
Definition An alpha- and gamma-adaptin-binding protein p34 that is encoded in the genome of human.
Short Label hAAGAB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PD74 (AAGAB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S118 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K293 Acetylation PhosphoSitePlus
S310 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17081983, ...18669648, 19690332, 20068231
S311 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17081983, ...18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S310 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S311 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S118 Y118 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K177 T177 Biomuta DOID:363 / uterine cancer [ icgc ]
K270 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S310 L310 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]