iPTMnet Report Q6PCE3 PGM2L1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q6PCE3 / PGM2L_HUMAN
Protein Name	Glucose 1,6-bisphosphate synthase
Gene Name	Name: PGM2L1 Synonyms:BM32A;
Organism	Homo sapiens (Human)

PRO ID	PR:Q6PCE3 DAG View
PRO Name	glucose 1,6-bisphosphate synthase (human)
Definition	A glucose 1,6-bisphosphate synthase that is encoded in the genome of human.
Short Label	hPGM2L1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q6PCE3 (PGM2L1) as Substrate

Q6PCE3

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K42	Ubiquitination		score1	PhosphoSitePlus
	T69	Phosphorylation		score1	PhosphoSitePlus
	T134	Phosphorylation		score1	PhosphoSitePlus
	Y146	Phosphorylation		score1	PhosphoSitePlus
	Y159	Phosphorylation		score1	PhosphoSitePlus
	T173	Phosphorylation		score2	HPRD PhosphoSitePlus	17322306, 18767875, 19651622, ...20068231
	S175	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 21406692, 23186163, ...17081983, 18220336, 18767875, 19651622, 17322306, 18669648, 20166139, 18510355, 19415658, 20068231
	C303	S-Nitrosylation		score0	dbSNO	26338901
	S311	Phosphorylation		score1	PhosphoSitePlus
	S316	Phosphorylation		score1	PhosphoSitePlus
	K395	Ubiquitination		score1	PhosphoSitePlus
	K501	Methylation		score1	PhosphoSitePlus
	T532	Phosphorylation		score1	PhosphoSitePlus
	T533	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y159	*	Biomuta		DOID:4606 / bile duct cancer [ cosmic ]