iPTMnet Report for Q6P9H4 (CNKSR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P9H4 / CNKR3_HUMAN
Protein Name Connector enhancer of kinase suppressor of ras 3
Gene Name Name: CNKSR3
Synonyms:MAGI1;
Organism Homo sapiens (Human)

PRO ID PR:Q6P9H4
DAG View
PRO Name connector enhancer of kinase suppressor of ras 3 (human)
Definition A connector enhancer of kinase suppressor of ras 3 that is encoded in the genome of human.
Short Label hCNKSR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P9H4 (CNKSR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus   UniProt 23186163
T398 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
R483 Methylation PhosphoSitePlus
R495 Methylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T283 Phosphorylation HPRD 18491316
S383 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T283 S283 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R483 Q483 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R495 Q495 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R495 W495 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S514 R514 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]