iPTMnet Report for Q6P9B9 (INTS5)
Protein Information
| UniProt AC / UniProt ID | Q6P9B9 / INT5_HUMAN |
| Protein Name | Integrator complex subunit 5 |
| Gene Name | Name: INTS5 Synonyms:KIAA1698; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6P9B9 |
| PRO Name | integrator complex subunit 5 (human) |
| Definition | An integrator complex subunit 5 that is encoded in the genome of human. |
| Short Label | hINTS5 |
| Category | organism-gene |
DAG ViewQ6P9B9 (INTS5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330 | ||
| Y159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S279 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976 | ||
| K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C485 | Methylation | score1 | IEDB | 31844290 | ||
| T680 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K686 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C872 | Methylation | score1 | IEDB | 31844290 | ||
| S1010 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 15302935 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S267 | F267 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S268 | Y268 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S279 | F279 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T430 | N430 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C485 | G485 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T680 | I680 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] |
