iPTMnet Report for Q6P4E1 (GOLM2)
Protein Information
| UniProt AC / UniProt ID | Q6P4E1 / GOLM2_HUMAN |
| Protein Name | Protein GOLM2 |
| Gene Name | Name: GOLM2 Synonyms:CASC4;ORFNames:UNQ2573/PRO6308; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6P4E1 |
| PRO Name | protein GOLM2 (human) |
| Definition | A protein GOLM2 that is encoded in the genome of human. |
| Short Label | hGOLM2 |
| Category | organism-gene |
Q6P4E1 (GOLM2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378, 25732826 | ||
| N31 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S93 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| N114 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N115 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| N150 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| N151 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T152 | O-Glycosylation | score1 | GlyGen | 29485866, 33214551, 34019948, ... | ||
| Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T195 | O-Glycosylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S232 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
| S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S233 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
| S233 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K261 | Acetylation | score1 | PhosphoSitePlus | |||
| S275 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S275 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S277 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T312 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S313 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S328 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S332 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| T338 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T345 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S350 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S358 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S366 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S366 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231, 24275569 | ||
| S374 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S68 | W68 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S93 | R93 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| N115 | S115 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S232 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S277 | Y277 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S277 | C277 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| T312 | I312 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T312 | A312 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S328 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S332 | N332 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S350 | G350 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View