Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P444 / MTFR2_HUMAN
Protein Name Mitochondrial fission regulator 2
Gene Name Name: MTFR2
Synonyms:DUFD1,FAM54A;
Organism Homo sapiens (Human)

PRO ID PR:Q6P444
DAG View
PRO Name mitochondrial fission regulator 2 (human)
Definition A protein FAM54A that is encoded in the genome of human.
Short Label hMTFR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P444 (MTFR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 25944712
K43 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus   UniProt 23186163
K129 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
K278 Acetylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus   UniProt 23186163
S305 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K331 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S119 Phosphorylation HPRD 20068231
S154 Phosphorylation HPRD 20068231
S187 Phosphorylation HPRD 20068231
S328 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S119 P119 Biomuta DOID:1909 / melanoma [ cosmic ]
S314 C314 Biomuta DOID:1612 / breast cancer [ icgc ]
K320 N320 Biomuta DOID:1909 / melanoma [ cosmic ]
S354 * Biomuta DOID:3571 / liver cancer [ icgc ]
T378 I378 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S379 N379 Biomuta DOID:363 / uterine cancer [ tcga ]