iPTMnet Report for Q6P3X3 (TTC27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P3X3 / TTC27_HUMAN
Protein Name Tetratricopeptide repeat protein 27
Gene Name Name: TTC27
Organism Homo sapiens (Human)

PRO ID PR:Q6P3X3
DAG View
PRO Name tetratricopeptide repeat protein 27 (human)
Definition A tetratricopeptide repeat protein 27 that is encoded in the genome of human.
Short Label hTTC27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P3X3 (TTC27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
C624 Methylation IEDB 31844290
Y662 Phosphorylation PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus
Y715 Phosphorylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K742 Ubiquitination PhosphoSitePlus
K752 Acetylation PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K273 N273 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K517 R517 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K533 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y715 C715 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]