iPTMnet Report for Q6P2H3 (CEP85)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P2H3 / CEP85_HUMAN
Protein Name Centrosomal protein of 85 kDa
Gene Name Name: CEP85
Synonyms:CCDC21;
Organism Homo sapiens (Human)

PRO ID PR:Q6P2H3
DAG View
PRO Name centrosomal protein of 85 kDa (human)
Definition A centrosomal protein of 85 kDa that is encoded in the genome of human.
Short Label hCEP85
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P2H3 (CEP85) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T16 O-Glycosylation GlyGen 32938750
T16 Phosphorylation phospho.ELM 18669648
S17 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K25 Ubiquitination PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus   UniProt 23186163
K139 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y150 Phosphorylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
R206 Methylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K415 Acetylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
Y576 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus   UniProt 20068231
K633 Ubiquitination PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
C688 Methylation IEDB 31844290
T745 Phosphorylation PhosphoSitePlus
T746 Phosphorylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T16 Phosphorylation HPRD 18669648, 20068231
S17 Phosphorylation HPRD 18669648, 20068231
S141 Phosphorylation HPRD 20068231
Y576 Phosphorylation HPRD 19664994
S578 Phosphorylation HPRD 19664994
S623 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 F28 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S77 N77 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S97 F97 Biomuta DOID:1612 / breast cancer [ cosmic ]
S126 N126 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S141 F141 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S199 A199 Biomuta DOID:3571 / liver cancer [ cosmic ]
S215 N215 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y219 C219 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S264 F264 Biomuta DOID:4159 / skin cancer [ cosmic ]
K340 I340 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y576 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S578 L578 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]