iPTMnet Report for Q6P1N0 (CC2D1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P1N0 / C2D1A_HUMAN
Protein Name Coiled-coil and C2 domain-containing protein 1A
Gene Name Name: CC2D1A
Synonyms:AKI1;
Organism Homo sapiens (Human)

PRO ID PR:Q6P1N0
DAG View
PRO Name coiled-coil and C2 domain-containing protein 1A (human)
Definition A coiled-coil and C2 domain-containing protein 1A that is encoded in the genome of human.
Short Label hCC2D1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P1N0 (CC2D1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R13 Methylation PhosphoSitePlus
R19 Methylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
S118 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T120 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y147 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T204 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T206 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y207 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S208 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18220336, ...18847512, 20171170, 18669648, 20068231
T212 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S238 Phosphorylation phospho.ELM 18669648
S239 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S253 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K275 Ubiquitination PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus   UniProt 24275569
S327 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S455 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 20068231
T470 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
T478 Phosphorylation PhosphoSitePlus
T486 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
K711 Ubiquitination PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
K746 Ubiquitination PhosphoSitePlus
Y916 Phosphorylation PhosphoSitePlus
Y937 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T92 Phosphorylation HPRD 18452278
S118 Phosphorylation HPRD 18669648
T120 Phosphorylation HPRD 18669648, 20068231
S179 Phosphorylation HPRD 18491316
T204 Phosphorylation HPRD 18669648, 20068231
S208 Phosphorylation HPRD 18669648, 16964243, 20068231
S232 Phosphorylation HPRD 20068231
S238 Phosphorylation HPRD 18669648, 20068231
S239 Phosphorylation HPRD 18669648, 20068231
S253 Phosphorylation HPRD 18669648
S455 Phosphorylation HPRD 19651622, 18669648, 20068231
S475 Phosphorylation HPRD 18452278
T478 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T92 M92 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S179 F179 Biomuta DOID:4159 / skin cancer [ cosmic ]
T204 M204 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S327 L327 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S327 W327 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T334 M334 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K624 N624 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S674 F674 Biomuta DOID:4159 / skin cancer [ cosmic ]
S674 Y674 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K711 N711 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]