iPTMnet Report for Q6P1M3 (LLGL2)
Protein Information
| UniProt AC / UniProt ID | Q6P1M3 / L2GL2_HUMAN |
| Protein Name | LLGL scribble cell polarity complex component 2 |
| Gene Name | Name: LLGL2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6P1M3 |
| PRO Name | LLGL scribble cell polarity complex component 2 (human) |
| Definition | An LLGL scribble cell polarity complex component 2 that is encoded in the genome of human. |
| Short Label | hLLGL2 |
| Category | organism-gene |
DAG ViewQ6P1M3 (LLGL2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K281 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S453 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S480 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y499 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28114269 | ||
| S500 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K625 | Methylation | score1 | PhosphoSitePlus | |||
| K625 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K647 | Methylation | score1 | PhosphoSitePlus | |||
| S649 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S653 | Phosphorylation | score3 | neXtProt PhosphoSitePlus UniProt | 12725730 | ||
| S653 | Phosphorylation | P41743 (PRKCI) | score2 | neXtProt | 12725730 | |
| K666 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S680 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K682 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K724 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T737 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T741 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S802 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K826 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S847 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S916 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S961 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T963 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S965 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| K970 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S982 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K988 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1000 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1013 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1015 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T26 | M26 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S36 | N36 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S453 | L453 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K492 | N492 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S649 | A649 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S653 | P653 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S982 | G982 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K988 | M988 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K988 | T988 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
