iPTMnet Report for Q6P1L5 (FAM117B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P1L5 / F117B_HUMAN
Protein Name Protein FAM117B
Gene Name Name: FAM117B
Synonyms:ALS2CR13;
Organism Homo sapiens (Human)

PRO ID PR:Q6P1L5
DAG View
PRO Name protein FAM117B (human)
Definition A protein FAM117B that is encoded in the genome of human.
Short Label hFAM117B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P1L5 (FAM117B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus   UniProt 23186163
S16 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
K44 Methylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S156 Phosphorylation IEDB 29437277
S180 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus   UniProt 23186163
S212 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
T218 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S219 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S220 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
T223 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y228 Phosphorylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   UniProt 23186163
S276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
T335 O-Glycosylation GlyGen 23301498, 28657654
S345 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus   UniProt 19690332
T396 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
Y454 Phosphorylation PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus   UniProt 23186163
K467 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 19413330, 18767875, 20068231
T12 Phosphorylation HPRD 20068231
S16 Phosphorylation HPRD 19651622
T87 Phosphorylation HPRD 20068231
S89 Phosphorylation HPRD 20068231
S91 Phosphorylation HPRD 20068231
T92 Phosphorylation HPRD 20068231
S93 Phosphorylation HPRD 20068231
T95 Phosphorylation HPRD 20068231
S106 Phosphorylation HPRD 19413330
S219 Phosphorylation HPRD 18669648
S220 Phosphorylation HPRD 18669648
T223 Phosphorylation HPRD 18669648
S271 Phosphorylation HPRD 19664995
S273 Phosphorylation HPRD 19413330, 18767875, 19664994, ...19664995, 20068231
S449 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 F16 Biomuta [ cosmic ]
T95 P95 Biomuta DOID:1324 / lung cancer [ cosmic ]
T105 S105 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S128 G128 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S180 A180 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S187 L187 Biomuta DOID:1324 / lung cancer [ cosmic ]
S212 F212 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S213 I213 Biomuta DOID:1324 / lung cancer [ cosmic ]
S219 F219 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y228 C228 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y228 F228 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S261 T261 Biomuta DOID:1324 / lung cancer [ cosmic ]
S267 P267 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T389 K389 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T396 M396 Biomuta DOID:363 / uterine cancer [ icgc ]
S404 R404 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y454 H454 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S457 L457 Biomuta DOID:1612 / breast cancer [ icgc ]
S484 W484 Biomuta DOID:1612 / breast cancer [ cosmic ]