Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P1K8 / T2H2L_HUMAN
Protein Name General transcription factor IIH subunit 2-like protein
Gene Name Name: GTF2H2C_2
Synonyms:GTF2H2D;
Organism Homo sapiens (Human)

PRO ID PR:Q6P1K8
DAG View
PRO Name general transcription factor IIH subunit 2-like protein (human)
Definition A protein that is a translation product of any of the following genes in human: GTF2H2C/GTF2H2C_2.
Short Label hGTF2H2C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P1K8 (GTF2H2C_2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K40 Methylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y90 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K126 Q126 Biomuta DOID:4362 / cervical cancer [ tcga ]