Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NYC1 / JMJD6_HUMAN
Protein Name Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Gene Name Name: JMJD6
Synonyms:KIAA0585,PSR;
Organism Homo sapiens (Human)

PRO ID PR:Q6NYC1
DAG View
PRO Name bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (human)
Definition A bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 that is encoded in the genome of human.
Short Label hJMJD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NYC1 (JMJD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus   UniProt 23186163
K68 Ubiquitination PhosphoSitePlus
K100 Methylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K154 Sumoylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
T379 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K68 N68 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K154 T154 Biomuta DOID:1612 / breast cancer [ cosmic ]
T379 M379 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S381 R381 Biomuta DOID:3571 / liver cancer [ icgc ]
S390 A390 Biomuta DOID:1909 / melanoma [ tcga ]