iPTMnet Report for Q6NXT6 (TAPT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NXT6 / TAPT1_HUMAN
Protein Name Transmembrane anterior posterior transformation protein 1 homolog
Gene Name Name: TAPT1
Synonyms:CMVFR;
Organism Homo sapiens (Human)

PRO ID PR:Q6NXT6
DAG View
PRO Name transmembrane anterior posterior transformation protein 1 homolog (human)
Definition A transmembrane anterior posterior transformation protein 1 that is encoded in the genome of human.
Short Label hTAPT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NXT6 (TAPT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S75 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
T475 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus   UniProt 24275569
T529 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T538 Phosphorylation HPRD 18669648
S542 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K90 R90 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S377 R377 Biomuta DOID:3571 / liver cancer [ cosmic ]
T520 A520 Biomuta DOID:1319 / brain cancer [ cosmic ]
T529 I529 Biomuta DOID:363 / uterine cancer [ icgc ]
T538 M538 Biomuta DOID:1324 / lung cancer [ cosmic ]
S542 Y542 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]