iPTMnet Report for Q6NXT2 (H3-5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NXT2 / H3C_HUMAN
Protein Name Histone H3.3C
Gene Name Name: H3-5
Synonyms:H3F3C;
Organism Homo sapiens (Human)

PRO ID PR:Q6NXT2
DAG View
PRO Name histone H3.3C (human)
Definition A histone H3.3C that is encoded in the genome of human.
Short Label hH3-5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NXT2 (H3-5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PRO 15851689
S57 Phosphorylation UniProt 20850016
T80 O-Glycosylation GlyGen 21224338
T80 Phosphorylation UniProt 20850016
T118 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000045314 (hH3F3C/InitMet-/Phos:1) pS32 PRO 15851689


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 T32 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S57 T57 Biomuta DOID:1324 / lung cancer [ cosmic ]
S57 L57 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T80 I80 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T80 A80 Biomuta DOID:1324 / lung cancer [ cosmic ]
T118 A118 Biomuta DOID:4606 / bile duct cancer [ cosmic ]