iPTMnet Report for Q6NXS1 (PPP1R2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NXS1 / IPP2B_HUMAN
Protein Name Protein phosphatase inhibitor 2 family member B
Gene Name Name: PPP1R2B
Synonyms:PPP1R2P3;
Organism Homo sapiens (Human)

PRO ID PR:Q6NXS1
DAG View
PRO Name protein phosphatase inhibitor 2 family member B (human)
Definition A protein that is a translation product of the PPP1R2B gene in human.
Short Label hPPP1R2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NXS1 (PPP1R2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus   UniProt 23506001
S122 Phosphorylation PhosphoSitePlus   UniProt 23506001
S127 Phosphorylation PhosphoSitePlus   UniProt 23506001
S130 Phosphorylation PhosphoSitePlus
K145 Acetylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
K155 Acetylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 N35 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S130 L130 Biomuta DOID:4159 / skin cancer [ cosmic ]