iPTMnet Report for Q6NXG1 (ESRP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NXG1 / ESRP1_HUMAN
Protein Name Epithelial splicing regulatory protein 1
Gene Name Name: ESRP1
Synonyms:RBM35A;
Organism Homo sapiens (Human)

PRO ID PR:Q6NXG1
DAG View
PRO Name epithelial splicing regulatory protein 1 (human)
Definition An epithelial splicing regulatory protein 1 that is encoded in the genome of human.
Short Label hESRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NXG1 (ESRP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T225 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
Y573 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
R582 Methylation PhosphoSitePlus   UniProt 24129315
R636 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S543 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S237 L237 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S237 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K307 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T426 I426 Biomuta DOID:3571 / liver cancer [ cosmic ]
S543 F543 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T568 A568 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S576 P576 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R582 Q582 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]