iPTMnet Report for Q6NWY9 (PRPF40B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NWY9 / PR40B_HUMAN
Protein Name Pre-mRNA-processing factor 40 homolog B
Gene Name Name: PRPF40B
Synonyms:HYPC;
Organism Homo sapiens (Human)

PRO ID PR:Q6NWY9
DAG View
PRO Name pre-mRNA-processing factor 40 homolog B (human)
Definition A pre-mRNA-processing factor 40 homolog B that is encoded in the genome of human.
Short Label hPRPF40B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NWY9 (PRPF40B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K148 Acetylation PhosphoSitePlus   UniProt 19608861
K316 Acetylation PhosphoSitePlus
K563 Acetylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S767 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
R821 Methylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus   UniProt 23186163
S847 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S751 Phosphorylation HPRD 19651622
S797 Phosphorylation HPRD 18452278
S819 Phosphorylation HPRD 19651622
S836 Phosphorylation HPRD 18452278
S839 Phosphorylation HPRD 15302935, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R821 K821 Biomuta DOID:3571 / liver cancer [ cosmic ]
S839 C839 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S852 C852 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]