iPTMnet Report for Q6NW34 (NEPRO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NW34 / NEPRO_HUMAN
Protein Name Nucleolus and neural progenitor protein
Gene Name Name: NEPRO
Synonyms:C3orf17;
Organism Homo sapiens (Human)

PRO ID PR:Q6NW34
DAG View
PRO Name nucleolus and neural progenitor protein (human)
Definition A nucleolus and neural progenitor protein that is encoded in the genome of human.
Short Label hNEPRO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NW34 (NEPRO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y198 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S265 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16565220, ...18669648, 20068231
K298 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K320 Methylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
S328 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K332 Methylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
C419 Methylation IEDB 31844290
K421 Ubiquitination PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S265 Phosphorylation HPRD 18691976, 19664995, 16565220, ...18669648, 20068231, 17924679
S328 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K253 T253 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S265 L265 Biomuta DOID:1324 / lung cancer [ cosmic ]
K298 N298 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T368 S368 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S473 F473 Biomuta DOID:4159 / skin cancer [ cosmic ]
K521 T521 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]