iPTMnet Report for Q6NUQ4 (TMEM214)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NUQ4 / TM214_HUMAN
Protein Name Transmembrane protein 214
Gene Name Name: TMEM214
ORFNames:PP446;
Organism Homo sapiens (Human)

PRO ID PR:Q6NUQ4
DAG View
PRO Name transmembrane protein 214 (human)
Definition A transmembrane protein 214 that is encoded in the genome of human.
Short Label hTMEM214
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NUQ4 (TMEM214) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K4 Ubiquitination PhosphoSitePlus
R18 Methylation PhosphoSitePlus
R19 Methylation PhosphoSitePlus
R29 Methylation PhosphoSitePlus
R33 Methylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
K69 Methylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
C200 Methylation IEDB 31844290
K240 Ubiquitination PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
C529 S-Nitrosylation dbSNO 2212679, 22126794
C655 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
Y47 Phosphorylation HPRD 20068231
T50 Phosphorylation HPRD 20068231
T56 Phosphorylation HPRD 20068231
S57 Phosphorylation HPRD 20068231
Y60 Phosphorylation HPRD 20068231
T97 Phosphorylation HPRD 19651622, 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y47 Phosphorylation HPRD 20068231
T50 Phosphorylation HPRD 20068231
T56 Phosphorylation HPRD 20068231
S57 Phosphorylation HPRD 20068231
Y60 Phosphorylation HPRD 20068231
T97 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S57 N57 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T97 N97 Biomuta DOID:363 / uterine cancer [ icgc, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
K453 N453 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]