iPTMnet Report for Q6NUK4 (REEP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NUK4 / REEP3_HUMAN
Protein Name Receptor expression-enhancing protein 3
Gene Name Name: REEP3
Synonyms:C10orf74;
Organism Homo sapiens (Human)

PRO ID PR:Q6NUK4
DAG View
PRO Name receptor expression-enhancing protein 3 (human)
Definition A receptor expression-enhancing protein 3 that is encoded in the genome of human.
Short Label hREEP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NUK4 (REEP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S150 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S152 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T157 Phosphorylation phospho.ELM 18669648
T158 Phosphorylation phospho.ELM 18669648
Y170 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T201 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
Y209 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S210 Phosphorylation PhosphoSitePlus   UniProt 21406692
T216 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
K244 Methylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S150 Phosphorylation HPRD 20166139, 18669648
S152 Phosphorylation HPRD 20166139, 18669648
T157 Phosphorylation HPRD 18669648
T158 Phosphorylation HPRD 18669648
T201 Phosphorylation HPRD 19651622, 18669648
Y209 Phosphorylation HPRD 18669648
S210 Phosphorylation HPRD 19651622, 17081983
T216 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S187 T187 Biomuta [ cosmic ]