iPTMnet Report for Q6NUJ5 (PWWP2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NUJ5 / PWP2B_HUMAN
Protein Name PWWP domain-containing protein 2B
Gene Name Name: PWWP2B
Synonyms:PWWP2;
Organism Homo sapiens (Human)

PRO ID PR:Q6NUJ5
DAG View
PRO Name PWWP domain-containing protein 2B (human)
Definition A PWWP domain-containing protein 2B that is encoded in the genome of human.
Short Label hPWWP2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NUJ5 (PWWP2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus   UniProt 23186163
S167 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
S186 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S191 Phosphorylation PhosphoSitePlus
S206 Phosphorylation IEDB   PhosphoSitePlus   UniProt 35494241, 23186163
S250 Phosphorylation PhosphoSitePlus   UniProt 23186163
T259 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus   UniProt 23186163
S476 Phosphorylation PhosphoSitePlus
K558 Acetylation PhosphoSitePlus
K559 Acetylation PhosphoSitePlus
K565 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S167 Phosphorylation HPRD 20068231
T168 Phosphorylation HPRD 20068231
S186 Phosphorylation HPRD 15302935
S271 Phosphorylation HPRD 20068231
S291 Phosphorylation HPRD 17525332
Site PTM Type PTM Enzyme Score Source PMID
S167 Phosphorylation HPRD 20068231
T168 Phosphorylation HPRD 20068231
S186 Phosphorylation HPRD 15302935
S271 Phosphorylation HPRD 20068231
S291 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T168 I168 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T259 M259 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S447 L447 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S476 N476 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]