iPTMnet Report for Q6NTE8 (MRNIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NTE8 / MRNIP_HUMAN
Protein Name MRN complex-interacting protein
Gene Name Name: MRNIP
Synonyms:C5orf45;
Organism Homo sapiens (Human)

PRO ID PR:Q6NTE8
DAG View
PRO Name MRN complex-interacting protein (human)
Definition An MRN complex-interacting protein that is encoded in the genome of human.
Short Label hMRNIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NTE8 (MRNIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K58 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus   UniProt 27568553
S115 Phosphorylation PhosphoSitePlus   UniProt 27568553
K129 Ubiquitination PhosphoSitePlus
K134 Methylation PhosphoSitePlus
R141 Methylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
R278 Methylation PhosphoSitePlus
R287 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S259 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S100 L100 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ]
R141 H141 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
R141 C141 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S240 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R287 Q287 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R287 W287 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]