iPTMnet Report for Q6NT76 (HMBOX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NT76 / HMBX1_HUMAN
Protein Name Homeobox-containing protein 1
Gene Name Name: HMBOX1
Synonyms:HOT1;
Organism Homo sapiens (Human)

PRO ID PR:Q6NT76
DAG View
PRO Name homeobox-containing protein 1 (human)
Definition A homeobox-containing protein 1 that is encoded in the genome of human.
Short Label hHMBOX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NT76 (HMBOX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S126 Phosphorylation PhosphoSitePlus
T127 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus   UniProt 23186163
S152 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus   UniProt 23186163
S187 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K413 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S148 Phosphorylation HPRD 20068231
S152 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S187 F187 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T253 M253 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K314 N314 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S316 P316 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]