iPTMnet Report for Q6MZP7 (LIN54)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6MZP7 / LIN54_HUMAN
Protein Name Protein lin-54 homolog
Gene Name Name: LIN54
Synonyms:CXCDC1,KIAA2037;
Organism Homo sapiens (Human)

PRO ID PR:Q6MZP7
DAG View
PRO Name protein lin-54 homolog (human)
Definition A protein lin-54 that is encoded in the genome of human.
Short Label hLIN54
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6MZP7 (LIN54) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K92 Acetylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
S238 O-Glycosylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
K244 Acetylation PhosphoSitePlus   UniProt 19608861
K249 Acetylation PhosphoSitePlus   UniProt 19608861
K249 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus   UniProt 23186163
S274 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus   UniProt 23186163
S299 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 18220336
K313 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 18220336
K357 Acetylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
R435 Methylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus   UniProt 23186163
K639 Sumoylation PhosphoSitePlus
K639 Ubiquitination PhosphoSitePlus
T640 Phosphorylation PhosphoSitePlus
K661 Sumoylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
T671 Phosphorylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
K715 Acetylation PhosphoSitePlus
K741 Sumoylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S148 Phosphorylation HPRD 18669648
S150 Phosphorylation HPRD 18669648
S264 Phosphorylation HPRD 20068231
S274 Phosphorylation HPRD 18077418
T277 Phosphorylation HPRD 20068231
T280 Phosphorylation HPRD 19664995, 20068231
S282 Phosphorylation HPRD 19413330
S310 Phosphorylation HPRD 19651622, 18669648, 20068231
S314 Phosphorylation HPRD 19651622, 18669648, 20068231
S635 Phosphorylation HPRD 19651622, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K101 Q101 Biomuta DOID:3070 / malignant glioma [ tcga ]
T235 M235 Biomuta DOID:0070003 / blastoma [ cosmic ]
S238 C238 Biomuta DOID:8618 / oral cavity cancer [ icgc ]
T243 K243 Biomuta DOID:3571 / liver cancer [ icgc ]
T243 M243 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S310 L310 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R435 W435 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K582 E582 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K741 T741 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]