iPTMnet Report for Q6MZP7 (LIN54)
Protein Information
UniProt AC / UniProt ID | Q6MZP7 / LIN54_HUMAN |
Protein Name | Protein lin-54 homolog |
Gene Name | Name: LIN54 Synonyms:CXCDC1,KIAA2037; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6MZP7 |
PRO Name | protein lin-54 homolog (human) |
Definition | A protein lin-54 that is encoded in the genome of human. |
Short Label | hLIN54 |
Category | organism-gene |
Q6MZP7 (LIN54) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K92 | Acetylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
T106 | Phosphorylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
T235 | Phosphorylation | score1 | PhosphoSitePlus | |||
S238 | O-Glycosylation | score1 | PhosphoSitePlus | |||
T243 | Phosphorylation | score1 | PhosphoSitePlus | |||
K244 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K249 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
T277 | Phosphorylation | score1 | PhosphoSitePlus | |||
T280 | Phosphorylation | score1 | PhosphoSitePlus | |||
S282 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
S310 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231, 18220336 | ||
K313 | Ubiquitination | score1 | PhosphoSitePlus | |||
S314 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231, 18220336 | ||
K357 | Acetylation | score1 | PhosphoSitePlus | |||
K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
S371 | Phosphorylation | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
R435 | Methylation | score1 | PhosphoSitePlus | |||
K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
K569 | Ubiquitination | score1 | PhosphoSitePlus | |||
K580 | Ubiquitination | score1 | PhosphoSitePlus | |||
K582 | Ubiquitination | score1 | PhosphoSitePlus | |||
K608 | Ubiquitination | score1 | PhosphoSitePlus | |||
S635 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K639 | Sumoylation | score1 | PhosphoSitePlus | |||
K639 | Ubiquitination | score1 | PhosphoSitePlus | |||
T640 | Phosphorylation | score1 | PhosphoSitePlus | |||
K661 | Sumoylation | score1 | PhosphoSitePlus | |||
K661 | Ubiquitination | score1 | PhosphoSitePlus | |||
S667 | Phosphorylation | score1 | PhosphoSitePlus | |||
T671 | Phosphorylation | score1 | PhosphoSitePlus | |||
K683 | Ubiquitination | score1 | PhosphoSitePlus | |||
K715 | Acetylation | score1 | PhosphoSitePlus | |||
K741 | Sumoylation | score1 | PhosphoSitePlus | |||
K741 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S148 | Phosphorylation | score0 | HPRD | 18669648 | ||
S150 | Phosphorylation | score0 | HPRD | 18669648 | ||
S264 | Phosphorylation | score0 | HPRD | 20068231 | ||
S274 | Phosphorylation | score0 | HPRD | 18077418 | ||
T277 | Phosphorylation | score0 | HPRD | 20068231 | ||
T280 | Phosphorylation | score0 | HPRD | 19664995, 20068231 | ||
S282 | Phosphorylation | score0 | HPRD | 19413330 | ||
S310 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S314 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S635 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T14 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K101 | Q101 | Biomuta | DOID:3070 / malignant glioma [ tcga ] | |
T235 | M235 | Biomuta | DOID:0070003 / blastoma [ cosmic ] | |
S238 | C238 | Biomuta | DOID:8618 / oral cavity cancer [ icgc ] | |
T243 | K243 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
T243 | M243 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S310 | L310 | Biomuta | DOID:11934 / head and neck cancer [ tcga ] | |
R435 | W435 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, tcga ] | |
K582 | E582 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, tcga ] | |
K741 | T741 | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ] |