iPTMnet Report for Q6IS14 (EIF5AL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IS14 / IF5AL_HUMAN
Protein Name Eukaryotic translation initiation factor 5A-1-like
Gene Name Name: EIF5AL1
Organism Homo sapiens (Human)

PRO ID PR:Q6IS14
DAG View
PRO Name eukaryotic translation initiation factor 5A-1-like (human)
Definition A eukaryotic translation initiation factor 5A-1-like that is encoded in the genome of human.
Short Label hEIF5AL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IS14 (EIF5AL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
T17 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K27 Sumoylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
S44 O-Glycosylation GlyGen 30379171
K47 Ubiquitination PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K67 Acetylation PhosphoSitePlus
K67 Sumoylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K68 Methylation PhosphoSitePlus
K68 Sumoylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
Y69 Phosphorylation PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
K85 Sumoylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
R113 Methylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K67 N67 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K68 T68 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K85 R85 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
R113 H113 Biomuta [ cosmic ] DOID:363 / uterine cancer [ icgc ]
R113 C113 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K126 T126 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y127 S127 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y127 C127 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]