iPTMnet Report for Q6IQ49 (SDE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IQ49 / SDE2_HUMAN
Protein Name Splicing regulator SDE2 precursor
Gene Name Name: SDE2
Synonyms:C1orf55;
Organism Homo sapiens (Human)

PRO ID PR:Q6IQ49
DAG View
PRO Name splicing regulator SDE2 (human)
Definition A protein SDE2 homolog that is encoded in the genome of human.
Short Label hSDE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IQ49 (SDE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Ubiquitination PhosphoSitePlus
T61 O-Glycosylation GlyGen 23301498, 29351928
K94 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
K173 Methylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
R203 Methylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus   RLIMS-P 30698750
T274 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S278 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 20068231
T287 O-Glycosylation GlyGen 32938750
S297 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
T319 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 30698750, 17525332
K369 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T274 Phosphorylation HPRD 19651622, 18669648, 20068231
S278 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T319 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 T148 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S253 N253 Biomuta [ cosmic ]
S266 Y266 Biomuta DOID:9256 / colorectal cancer [ cosmic ]