iPTMnet Report for Q6IQ32 (ADNP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IQ32 / ADNP2_HUMAN
Protein Name Activity-dependent neuroprotector homeobox protein 2
Gene Name Name: ADNP2
Synonyms:KIAA0863,ZNF508;
Organism Homo sapiens (Human)

PRO ID PR:Q6IQ32
DAG View
PRO Name activity-dependent neuroprotector homeobox protein 2 (human)
Definition An activity-dependent neuroprotector homeobox protein 2 that is encoded in the genome of human.
Short Label hADNP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IQ32 (ADNP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K39 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
Y80 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K731 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
S757 Phosphorylation IEDB 35494241
Y840 Phosphorylation PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
T866 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
K872 Ubiquitination PhosphoSitePlus
T906 Phosphorylation PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
S910 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
K979 Ubiquitination PhosphoSitePlus
K1018 Acetylation PhosphoSitePlus
K1018 Ubiquitination PhosphoSitePlus
S1024 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1026 Phosphorylation PhosphoSitePlus
K1032 Sumoylation PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
K1044 Ubiquitination PhosphoSitePlus
Y1046 Phosphorylation PhosphoSitePlus
S1050 Phosphorylation PhosphoSitePlus
Y1051 Phosphorylation PhosphoSitePlus
K1055 Ubiquitination PhosphoSitePlus
K1059 Ubiquitination PhosphoSitePlus
Y1061 Phosphorylation PhosphoSitePlus
Y1067 Phosphorylation PhosphoSitePlus
K1093 Ubiquitination PhosphoSitePlus
K1119 Ubiquitination PhosphoSitePlus
Y1129 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K199 Q199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K199 I199 Biomuta DOID:1324 / lung cancer [ cosmic ]
K208 N208 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K256 E256 Biomuta DOID:3571 / liver cancer [ cosmic ]
K262 R262 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T906 M906 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K909 R909 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1129 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]