iPTMnet Report for Q6IQ23 (PLEKHA7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IQ23 / PKHA7_HUMAN
Protein Name Pleckstrin homology domain-containing family A member 7
Gene Name Name: PLEKHA7
Organism Homo sapiens (Human)

PRO ID PR:Q6IQ23
DAG View
PRO Name pleckstrin homology domain-containing family A member 7 (human)
Definition A pleckstrin homology domain-containing family A member 7 that is encoded in the genome of human.
Short Label hPLEKHA7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IQ23 (PLEKHA7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S117 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S121 O-Glycosylation GlyGen 30379171, 35254053
S121 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
Y412 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
T477 Phosphorylation IEDB 32387766
S481 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus   UniProt 24275569
T538 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus   UniProt 24275569
T589 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
S608 Phosphorylation PhosphoSitePlus   UniProt 24275569
S612 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332, 24275569
S624 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
Y656 Phosphorylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
K669 Ubiquitination PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
S858 Phosphorylation PhosphoSitePlus   UniProt 24275569
S860 Phosphorylation PhosphoSitePlus   UniProt 24275569
S867 Phosphorylation PhosphoSitePlus   UniProt 24275569
T870 Phosphorylation PhosphoSitePlus   UniProt 24275569
S871 Phosphorylation PhosphoSitePlus   UniProt 24275569
T875 Phosphorylation PhosphoSitePlus
T887 Phosphorylation PhosphoSitePlus
Y888 Phosphorylation PhosphoSitePlus
Y891 Phosphorylation PhosphoSitePlus
T902 Phosphorylation PhosphoSitePlus
S903 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15144186, ...18669648, 24275569, 19690332
S907 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332
T909 Phosphorylation phospho.ELM   PhosphoSitePlus 15144186
S930 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
S983 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus   UniProt 19690332
T992 Phosphorylation PhosphoSitePlus
Y1011 Phosphorylation PhosphoSitePlus
T1013 Phosphorylation PhosphoSitePlus
R1017 Methylation PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus
T1023 Phosphorylation PhosphoSitePlus
Y1035 Phosphorylation PhosphoSitePlus
T1037 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
Y1062 Phosphorylation PhosphoSitePlus
S1063 Phosphorylation PhosphoSitePlus
T1094 Phosphorylation PhosphoSitePlus
S1110 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y470 Phosphorylation HPRD 19901323
S612 Phosphorylation HPRD 19664995
S903 Phosphorylation HPRD 19413330, 20166139, 18669648, ...19664994
S907 Phosphorylation HPRD 19413330, 20166139, 18669648, ...19664994
T909 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S117 P117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S118 R118 Biomuta DOID:3571 / liver cancer [ cosmic ]
S118 I118 Biomuta DOID:263 / kidney cancer [ cosmic ]
T123 A123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T123 I123 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T125 M125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y243 C243 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S363 Y363 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T454 M454 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S465 P465 Biomuta DOID:363 / uterine cancer [ icgc ]
T472 N472 Biomuta DOID:3571 / liver cancer [ cosmic ]
S481 L481 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S485 L485 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
S536 R536 Biomuta DOID:1612 / breast cancer [ icgc ]
T538 I538 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S565 Y565 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S608 L608 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S612 F612 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S624 L624 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S625 F625 Biomuta DOID:1319 / brain cancer [ icgc ]
K669 N669 Biomuta DOID:1324 / lung cancer [ cosmic ]
K669 R669 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T870 I870 Biomuta DOID:4159 / skin cancer [ cosmic ]
T870 N870 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S903 F903 Biomuta DOID:4159 / skin cancer [ cosmic ]
S903 P903 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T992 A992 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1013 M1013 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1022 F1022 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]