Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IN85 / P4R3A_HUMAN
Protein Name Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Gene Name Name: PPP4R3A
Synonyms:KIAA2010,PP4R3A,SMEK1;ORFNames:MSTP033;
Organism Homo sapiens (Human)

PRO ID PR:Q6IN85
DAG View
PRO Name serine/threonine-protein phosphatase 4 regulatory subunit 3A (human)
Definition A serine/threonine-protein phosphatase 4 regulatory subunit 3A that is encoded in the genome of human.
Short Label hPPP4R3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IN85 (PPP4R3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
R17 Methylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S117 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S126 Phosphorylation PhosphoSitePlus
S127 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S153 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
Y573 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
Y633 Phosphorylation PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K655 Acetylation PhosphoSitePlus   UniProt 19608861
K655 Methylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
T674 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
S698 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S700 Phosphorylation PhosphoSitePlus
T703 Phosphorylation PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
K733 Methylation PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S743 Phosphorylation PhosphoSitePlus
T757 Phosphorylation PhosphoSitePlus
S768 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S771 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S774 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S777 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332
S780 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S783 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S789 Phosphorylation PhosphoSitePlus
Y806 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S54 L54 Biomuta DOID:1612 / breast cancer [ tcga ]
S117 F117 Biomuta DOID:4362 / cervical cancer [ tcga ]
T685 K685 Biomuta DOID:3571 / liver cancer [ icgc ]
S741 N741 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S743 G743 Biomuta DOID:0070003 / blastoma [ cosmic ]
S774 F774 Biomuta DOID:1324 / lung cancer [ cosmic ]
S780 F780 Biomuta DOID:363 / uterine cancer [ tcga ]
Y806 C806 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]