iPTMnet Report for Q6IBW4 (NCAPH2)
Protein Information
| UniProt AC / UniProt ID | Q6IBW4 / CNDH2_HUMAN |
| Protein Name | Condensin-2 complex subunit H2 |
| Gene Name | Name: NCAPH2 Synonyms:CAPH2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6IBW4 |
| PRO Name | condensin-2 complex subunit H2 (human) |
| Definition | A condensin-2 complex subunit H2 that is encoded in the genome of human. |
| Short Label | hNCAPH2 |
| Category | organism-gene |
Q6IBW4 (NCAPH2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| T19 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S95 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K134 | Sumoylation | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S208 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332, 20068231 | ||
| T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C230 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S282 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
| S284 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163, 20068231 | ||
| S288 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28717250 | ||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S319 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28717250 | ||
| S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K329 | Sumoylation | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K333 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C342 | Methylation | score1 | IEDB | 31844290 | ||
| K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T403 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S428 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S464 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S466 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| T489 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S492 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 24934155, 17525332, 23186163, ... | ||
| T501 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28717250 | ||
| T568 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y597 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S601 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T19 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S95 | Phosphorylation | score0 | HPRD | 19691289, 20068231, 16565220 | ||
| S96 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| S120 | Phosphorylation | score0 | HPRD | 20068231, 16565220 | ||
| S127 | Phosphorylation | score0 | HPRD | 16565220 | ||
| T138 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S140 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S200 | Phosphorylation | score0 | HPRD | 20068231, 16565220 | ||
| S208 | Phosphorylation | score0 | HPRD | 16565220, 15302935, 20068231, ... | ||
| T213 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S228 | Phosphorylation | score0 | HPRD | 19691289, 16565220 | ||
| S232 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S246 | Phosphorylation | score0 | HPRD | 18669648, 18452278 | ||
| S282 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 19691289, ... | ||
| S284 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18212344, ... | ||
| S288 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S308 | Phosphorylation | score0 | HPRD | 19691289 | ||
| S319 | Phosphorylation | score0 | HPRD | 16565220 | ||
| S325 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S464 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S466 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 16565220 | ||
| T489 | Phosphorylation | score0 | HPRD | 19691289 | ||
| S492 | Phosphorylation | score0 | HPRD | 18691976, 18077418, 19691289, ... |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T19 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S95 | Phosphorylation | score0 | HPRD | 19691289, 20068231, 16565220 | ||
| S96 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| S120 | Phosphorylation | score0 | HPRD | 20068231, 16565220 | ||
| S127 | Phosphorylation | score0 | HPRD | 16565220 | ||
| T138 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S140 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S200 | Phosphorylation | score0 | HPRD | 20068231, 16565220 | ||
| S208 | Phosphorylation | score0 | HPRD | 16565220, 15302935, 20068231, ... | ||
| T213 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S228 | Phosphorylation | score0 | HPRD | 19691289, 16565220 | ||
| S232 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S246 | Phosphorylation | score0 | HPRD | 18669648, 18452278 | ||
| S284 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 16565220 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S120 | P120 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S120 | L120 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| T183 | M183 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S200 | P200 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S208 | Y208 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S208 | F208 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| C230 | Y230 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S246 | C246 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S282 | F282 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| S385 | F385 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S428 | C428 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic, cosmic ] |
DAG View