iPTMnet Report for Q6IA17 (SIGIRR)
Protein Information
UniProt AC / UniProt ID | Q6IA17 / SIGIR_HUMAN |
Protein Name | Single Ig IL-1-related receptor |
Gene Name | Name: SIGIRR ORFNames:UNQ301/PRO342; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6IA17 |
PRO Name | single Ig IL-1-related receptor (human) |
Definition | A single Ig IL-1-related receptor that is encoded in the genome of human. |
Short Label | hSIGIRR |
Category | organism-gene |
Q6IA17 (SIGIRR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y395 | Phosphorylation | score1 | PhosphoSitePlus | |||
S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
T399 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y402 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S364 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S388 | L388 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S392 | L392 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |