iPTMnet Report for Q6I9Y2 (THOC7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6I9Y2 / THOC7_HUMAN
Protein Name THO complex subunit 7 homolog
Gene Name Name: THOC7
Synonyms:NIF3L1BP1;
Organism Homo sapiens (Human)

PRO ID PR:Q6I9Y2
DAG View
PRO Name THO complex subunit 7 homolog (human)
Definition A THO complex subunit 7 that is encoded in the genome of human.
Short Label hTHOC7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6I9Y2 (THOC7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 19413330, 25489052
T5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K32 Acetylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus   UniProt 19608861
K36 Ubiquitination PhosphoSitePlus
C60 Methylation IEDB 31844290
K83 Ubiquitination PhosphoSitePlus
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
C90 Methylation IEDB 31844290
K98 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S155 Phosphorylation HPRD   PhosphoSitePlus 20068231
K159 Ubiquitination PhosphoSitePlus
S188 Phosphorylation HPRD 20068231
S197 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K104 R104 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K137 N137 Biomuta DOID:1324 / lung cancer [ cosmic ]
K159 N159 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S188 T188 Biomuta DOID:1324 / lung cancer [ cosmic ]
S188 P188 Biomuta DOID:4159 / skin cancer [ cosmic ]
S197 R197 Biomuta DOID:3571 / liver cancer [ cosmic ]