Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6HA08 / ASTL_HUMAN
Protein Name Astacin-like metalloendopeptidase precursor
Gene Name Name: ASTL
Organism Homo sapiens (Human)

PRO ID PR:Q6HA08
DAG View
PRO Name astacin-like metalloendopeptidase (human)
Definition An astacin-like metalloendopeptidase that is encoded in the genome of human.
Short Label hASTL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6HA08 (ASTL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S99 N99 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S156 I156 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S156 T156 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S244 R244 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ] DOID:3571 / liver cancer [ icgc ]