iPTMnet Report for Q6GYQ0 (RALGAPA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6GYQ0 / RGPA1_HUMAN
Protein Name Ral GTPase-activating protein subunit alpha-1
Gene Name Name: RALGAPA1
Synonyms:GARNL1,KIAA0884,TULIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q6GYQ0
DAG View
PRO Name Ral GTPase-activating protein subunit alpha-1 (human)
Definition A Ral GTPase-activating protein subunit alpha-1 that is encoded in the genome of human.
Short Label hRALGAPA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6GYQ0 (RALGAPA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
T611 Phosphorylation PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus   UniProt 23186163
K714 Acetylation PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus   UniProt 23186163
S734 Phosphorylation PhosphoSitePlus
T736 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
T743 Phosphorylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
T754 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...20068231
S773 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18220336, ...18669648, 20068231
S775 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T778 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S795 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...18220336
T798 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S853 Phosphorylation PhosphoSitePlus
S860 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 23186163, ...17081983
S861 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 23186163, ...17081983
S864 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S958 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus   UniProt 24275569
S990 Phosphorylation PhosphoSitePlus   UniProt 24275569
S994 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1000 Phosphorylation PhosphoSitePlus
T1002 Phosphorylation PhosphoSitePlus
S1004 Phosphorylation PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
T1007 Phosphorylation PhosphoSitePlus
K1133 Methylation PhosphoSitePlus
S1324 Phosphorylation PhosphoSitePlus
T1368 Phosphorylation PhosphoSitePlus
T1370 Phosphorylation PhosphoSitePlus
S1478 O-Glycosylation GlyGen 29351928
S1478 Phosphorylation PhosphoSitePlus
S1554 Phosphorylation PhosphoSitePlus
T1565 Phosphorylation PhosphoSitePlus
S1569 Phosphorylation PhosphoSitePlus
S1575 Phosphorylation PhosphoSitePlus
S1585 Phosphorylation PhosphoSitePlus
S1590 Phosphorylation PhosphoSitePlus
S1593 Phosphorylation PhosphoSitePlus
Y1614 Phosphorylation PhosphoSitePlus
S1658 Phosphorylation PhosphoSitePlus
T1673 Phosphorylation PhosphoSitePlus
S1776 Phosphorylation PhosphoSitePlus
S1782 Phosphorylation PhosphoSitePlus
S1801 Phosphorylation PhosphoSitePlus
T1807 Phosphorylation PhosphoSitePlus
S1942 Phosphorylation PhosphoSitePlus
K1984 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S740 Phosphorylation HPRD 20068231
T754 Phosphorylation HPRD 18669648, 20068231
S773 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
S775 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T778 Phosphorylation HPRD 18669648, 17081983
S795 Phosphorylation HPRD 20230923
S796 Phosphorylation HPRD 20230923
S797 Phosphorylation HPRD 20230923, 20058876, 19651622, ...18669648, 19415658, 20068231
T798 Phosphorylation HPRD 20230923
S860 Phosphorylation HPRD 19651622, 18669648, 19664994, ...17081983, 20068231
S861 Phosphorylation HPRD 19651622, 18669648, 19664994, ...17081983, 20068231
S864 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S740 Phosphorylation HPRD 20068231
T754 Phosphorylation HPRD 18669648, 20068231
S773 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
S775 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T778 Phosphorylation HPRD 18669648, 17081983
S795 Phosphorylation HPRD 20230923
S796 Phosphorylation HPRD 20230923
S797 Phosphorylation HPRD 20230923, 20058876, 19651622, ...18669648, 19415658, 20068231
T798 Phosphorylation HPRD 20230923
S860 Phosphorylation HPRD 19651622, 18669648, 19664994, ...17081983, 20068231
S861 Phosphorylation HPRD 19651622, 18669648, 19664994, ...17081983, 20068231
S864 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S2070 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S798 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S342 I342 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S368 C368 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S503 F503 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S711 L711 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T743 I743 Biomuta DOID:4159 / skin cancer [ cosmic ]
S748 I748 Biomuta DOID:1324 / lung cancer [ cosmic ]
S773 L773 Biomuta DOID:4362 / cervical cancer [ icgc ]
S849 G849 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S990 F990 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ icgc ]
T1002 S1002 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1324 F1324 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1368 A1368 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1565 A1565 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]