Protein Information

Cytoscape View

UniProt AC / UniProt ID Q6GPH6 / IPIL1_HUMAN
Protein Name Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 precursor
Gene Name Name: ITPRIPL1
Organism Homo sapiens (Human)

DAG View
PRO Name inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 (human)
Definition An inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 that is encoded in the genome of human.
Short Label hITPRIPL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q6GPH6 (ITPRIPL1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K71 R71 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T77 A77 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
T77 P77 Biomuta DOID:2531 / hematologic cancer [ icgc ]