iPTMnet Report for Q6GPH4 (XAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6GPH4 / XAF1_HUMAN
Protein Name XIAP-associated factor 1
Gene Name Name: XAF1
Synonyms:BIRC4BP,XIAPAF1;
Organism Homo sapiens (Human)

PRO ID PR:Q6GPH4
DAG View
PRO Name XIAP-associated factor 1 (human)
Definition An XIAP-associated factor 1 that is encoded in the genome of human.
Short Label hXAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6GPH4 (XAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S70 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 L70 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y152 C152 Biomuta DOID:1324 / lung cancer [ cosmic ]
K180 T180 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]