iPTMnet Report for Q6F5E8 (CARMIL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6F5E8 / CARL2_HUMAN
Protein Name Capping protein, Arp2/3 and myosin-I linker protein 2
Gene Name Name: CARMIL2
Synonyms:LRRC16C,RLTPR;
Organism Homo sapiens (Human)

PRO ID PR:Q6F5E8
DAG View
PRO Name capping protein, Arp2/3 and myosin-I linker protein 2 (human)
Definition A capping protein, Arp2/3 and myosin-I linker protein 2 that is encoded in the genome of human.
Short Label hCARMIL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6F5E8 (CARMIL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
K126 Methylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S993 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1088 Phosphorylation PhosphoSitePlus
T1093 Phosphorylation PhosphoSitePlus
R1095 Methylation PhosphoSitePlus
K1105 Acetylation PhosphoSitePlus
K1106 Acetylation PhosphoSitePlus
T1115 O-Glycosylation GlyGen 23301498, 30379171, 34019948
T1119 Phosphorylation PhosphoSitePlus
S1120 Phosphorylation PhosphoSitePlus
S1157 Phosphorylation PhosphoSitePlus
Y1175 Phosphorylation PhosphoSitePlus
K1194 Ubiquitination PhosphoSitePlus
T1203 Phosphorylation PhosphoSitePlus
R1224 Methylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1246 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1268 Phosphorylation PhosphoSitePlus
S1281 Phosphorylation PhosphoSitePlus
S1315 Phosphorylation PhosphoSitePlus
S1319 Phosphorylation PhosphoSitePlus
S1321 Phosphorylation PhosphoSitePlus
T1325 Phosphorylation PhosphoSitePlus
S1326 Phosphorylation PhosphoSitePlus
S1328 Phosphorylation PhosphoSitePlus
S1331 Phosphorylation PhosphoSitePlus
S1355 Phosphorylation PhosphoSitePlus
S1362 Phosphorylation PhosphoSitePlus
S1381 Phosphorylation PhosphoSitePlus
S1395 Phosphorylation PhosphoSitePlus
S1397 Phosphorylation PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus
S1423 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S991 Phosphorylation HPRD 18669648
S993 Phosphorylation HPRD 20058876
S1246 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K563 R563 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S886 I886 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R1095 Q1095 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y1175 N1175 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1224 Q1224 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1331 N1331 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1331 C1331 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1381 F1381 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1395 F1395 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]