iPTMnet Report for Q6DN12 (MCTP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6DN12 / MCTP2_HUMAN
Protein Name Multiple C2 and transmembrane domain-containing protein 2
Gene Name Name: MCTP2
Organism Homo sapiens (Human)

PRO ID PR:Q6DN12
DAG View
PRO Name multiple C2 and transmembrane domain-containing protein 2 (human)
Definition A multiple C2 and transmembrane domain-containing protein 2 that is encoded in the genome of human.
Short Label hMCTP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6DN12 (MCTP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
K13 Methylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S134 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S135 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
T144 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T287 O-Glycosylation GlyGen 25813380
T288 O-Glycosylation GlyGen 25813380
S332 Phosphorylation PhosphoSitePlus
K335 Acetylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
Y496 Phosphorylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
S735 Phosphorylation phospho.ELM 18669648
T739 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y818 Phosphorylation PhosphoSitePlus
K856 Ubiquitination PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation HPRD 18669648
T144 Phosphorylation HPRD 17924679
S145 Phosphorylation HPRD 17924679
S735 Phosphorylation HPRD 18669648
T739 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S51 F51 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T288 I288 Biomuta DOID:3571 / liver cancer [ cosmic ]
S345 F345 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K350 N350 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T374 A374 Biomuta DOID:363 / uterine cancer [ icgc ]
Y496 H496 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S527 L527 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K608 E608 Biomuta DOID:4159 / skin cancer [ cosmic ]
S735 N735 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T739 I739 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K856 Q856 Biomuta DOID:1612 / breast cancer [ cosmic ]