iPTMnet Report for Q6AZZ1 (TRIM68)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6AZZ1 / TRI68_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM68
Gene Name Name: TRIM68
Synonyms:GC109,RNF137,SS56;
Organism Homo sapiens (Human)

PRO ID PR:Q6AZZ1
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM68 (human)
Definition An E3 ubiquitin-protein ligase TRIM68 that is encoded in the genome of human.
Short Label hTRIM68
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6AZZ1 (TRIM68) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C31 Methylation IEDB 31844290
K81 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
C479 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K161 N161 Biomuta DOID:1319 / brain cancer [ cosmic ]
T172 I172 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]