iPTMnet Report for Q6AWC2 (WWC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6AWC2 / WWC2_HUMAN
Protein Name Protein WWC2
Gene Name Name: WWC2
Synonyms:BOMB;
Organism Homo sapiens (Human)

PRO ID PR:Q6AWC2
DAG View
PRO Name protein WWC2 (human)
Definition A protein WWC2 that is encoded in the genome of human.
Short Label hWWC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6AWC2 (WWC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
T533 Phosphorylation PhosphoSitePlus
R707 Methylation PhosphoSitePlus
Y737 Phosphorylation PhosphoSitePlus
S984 Phosphorylation PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
S987 Phosphorylation PhosphoSitePlus
S1002 Phosphorylation PhosphoSitePlus
T1004 Phosphorylation PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
S1020 Phosphorylation PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
K1096 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S211 Phosphorylation HPRD 19664995
S1022 Phosphorylation HPRD 15302935, 20068231
Site PTM Type PTM Enzyme Score Source PMID
K917 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K328 Q328 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y470 H470 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R707 I707 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1006 Y1006 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]