Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6AI14 / SL9A4_HUMAN
Protein Name Sodium/hydrogen exchanger 4
Gene Name Name: SLC9A4
Synonyms:NHE4;
Organism Homo sapiens (Human)

PRO ID PR:Q6AI14
DAG View
PRO Name sodium/hydrogen exchanger 4 (human)
Definition A sodium/hydrogen exchanger 4 that is encoded in the genome of human.
Short Label hSLC9A4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6AI14 (SLC9A4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K352 Ubiquitination PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
Y613 Phosphorylation PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
T673 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T619 I619 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T634 I634 Biomuta DOID:2531 / hematologic cancer [ tcga ]
S724 I724 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]