iPTMnet Report for Q69YN4 (VIRMA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q69YN4 / VIR_HUMAN
Protein Name Protein virilizer homolog
Gene Name Name: VIRMA
Synonyms:KIAA1429;ORFNames:MSTP054;
Organism Homo sapiens (Human)

PRO ID PR:Q69YN4
DAG View
PRO Name protein virilizer homolog (human)
Definition A protein virilizer homolog that is encoded in the genome of human.
Short Label hVIRMA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q69YN4 (VIRMA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K16 Ubiquitination PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S138 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
S154 Phosphorylation PhosphoSitePlus
K166 Acetylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983
T184 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...24275569
S204 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus   UniProt 20068231
S235 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y355 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
T590 Phosphorylation PhosphoSitePlus
T660 Phosphorylation PhosphoSitePlus
K843 Acetylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
Y914 Phosphorylation PhosphoSitePlus   UniProt 19690332
T924 Phosphorylation PhosphoSitePlus
K1029 Ubiquitination PhosphoSitePlus
T1080 Phosphorylation PhosphoSitePlus
C1279 Methylation IEDB 31844290
K1380 Ubiquitination PhosphoSitePlus
S1432 O-Glycosylation GlyGen 25813380
S1432 Phosphorylation PhosphoSitePlus
K1445 Ubiquitination PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
K1458 Ubiquitination PhosphoSitePlus
S1464 Phosphorylation PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
S1561 Phosphorylation PhosphoSitePlus
S1572 Phosphorylation PhosphoSitePlus
S1575 Phosphorylation PhosphoSitePlus
S1578 Phosphorylation PhosphoSitePlus
S1579 Phosphorylation PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...19690332, 20068231
T1583 Phosphorylation PhosphoSitePlus
K1595 Ubiquitination PhosphoSitePlus
Y1608 Phosphorylation PhosphoSitePlus
R1626 Methylation PhosphoSitePlus
R1634 Methylation PhosphoSitePlus
T1646 Phosphorylation PhosphoSitePlus
S1647 Phosphorylation PhosphoSitePlus
S1651 Phosphorylation PhosphoSitePlus
K1663 Acetylation PhosphoSitePlus
R1687 Methylation PhosphoSitePlus
R1694 Methylation PhosphoSitePlus
R1697 Methylation PhosphoSitePlus
T1708 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1712 O-Glycosylation GlyGen 31373491
R1719 Methylation PhosphoSitePlus
R1723 Methylation PhosphoSitePlus   UniProt 24129315
S1728 Phosphorylation PhosphoSitePlus
T1732 Phosphorylation PhosphoSitePlus
R1734 Methylation PhosphoSitePlus
R1741 Methylation PhosphoSitePlus
R1749 Methylation PhosphoSitePlus
S1759 Phosphorylation PhosphoSitePlus
S1766 Phosphorylation PhosphoSitePlus
R1773 Methylation PhosphoSitePlus   UniProt 24129315
R1775 Methylation PhosphoSitePlus   UniProt 24129315
R1793 Methylation PhosphoSitePlus   UniProt 24129315
S1801 Phosphorylation PhosphoSitePlus
R1808 Methylation PhosphoSitePlus
R1812 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y36 Phosphorylation HPRD 19664994
T108 Phosphorylation HPRD 20068231
S133 Phosphorylation HPRD 19651622, 18669648, 20068231
S138 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S173 Phosphorylation HPRD 18767875, 17081983, 20068231
T184 Phosphorylation HPRD 17081983, 20068231, 18452278
S222 Phosphorylation HPRD 19651622, 19664994, 17081983, ...20068231, 18452278
S235 Phosphorylation HPRD 18452278
S302 Phosphorylation HPRD 18452278
S303 Phosphorylation HPRD 18452278
S1432 Phosphorylation HPRD 20068231
S1472 Phosphorylation HPRD 20068231
S1578 Phosphorylation HPRD 18691976, 20058876, 19664995, ...18452278, 19415658, 20068231
S1579 Phosphorylation HPRD 19413330, 20058876, 16964243, ...18767875, 15302935, 19664995, 18452278, 19651622, 18669648, 19415658, 20068231
T1583 Phosphorylation HPRD 20068231
S1647 Phosphorylation HPRD 20068231
T1708 Phosphorylation HPRD 18669648, 20068231
S1798 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y36 Phosphorylation HPRD 19664994
T108 Phosphorylation HPRD 20068231
S133 Phosphorylation HPRD 19651622, 18669648, 20068231
S138 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S173 Phosphorylation HPRD 18767875, 17081983, 20068231
T184 Phosphorylation HPRD 17081983, 20068231, 18452278
S222 Phosphorylation HPRD 19651622, 19664994, 17081983, ...20068231, 18452278
S235 Phosphorylation HPRD 18452278
S302 Phosphorylation HPRD 18452278
S303 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S89 R89 Biomuta DOID:3571 / liver cancer [ cosmic ]
S97 F97 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc, icgc ] DOID:8618 / oral cavity cancer [ cosmic, cosmic ] DOID:1319 / brain cancer [ cosmic ]
S138 F138 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S173 R173 Biomuta DOID:1319 / brain cancer [ cosmic ]
S173 I173 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S173 N173 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S302 F302 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S303 C303 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y355 C355 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K576 T576 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K843 N843 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1448 R1448 Biomuta DOID:363 / uterine cancer [ icgc ]
S1579 F1579 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y1608 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R1634 Q1634 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1634 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
S1651 F1651 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1687 H1687 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1694 T1694 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1712 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R1723 T1723 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T1732 N1732 Biomuta DOID:3571 / liver cancer [ cosmic ]
R1734 Q1734 Biomuta DOID:3571 / liver cancer [ cosmic ]
R1775 C1775 Biomuta [ cosmic ]
R1793 I1793 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1793 K1793 Biomuta DOID:1319 / brain cancer [ icgc ]
R1808 C1808 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R1808 H1808 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R1812 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]