Protein Information

Cytoscape View


UniProt AC / UniProt ID Q69YH5 / CDCA2_HUMAN
Protein Name Cell division cycle-associated protein 2
Gene Name Name: CDCA2
Organism Homo sapiens (Human)

PRO ID PR:Q69YH5
DAG View
PRO Name cell division cycle-associated protein 2 (human)
Definition A cell division cycle-associated protein 2 that is encoded in the genome of human.
Short Label hCDCA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q69YH5 (CDCA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Methylation PhosphoSitePlus
K13 Methylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
K52 Methylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
T68 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
R96 Methylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T101 Phosphorylation PhosphoSitePlus
R106 Methylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
K119 Methylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S126 Phosphorylation PhosphoSitePlus   UniProt 18669648
S128 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus   UniProt 18669648
Y135 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus   UniProt 23186163
K276 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus   UniProt 18669648
S301 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus   UniProt 18669648
T312 Phosphorylation PhosphoSitePlus   UniProt 18669648
K323 Ubiquitination PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
S407 Phosphorylation PhosphoSitePlus   UniProt 18669648
T412 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 18669648, 19690332, 21820363
K424 Ubiquitination PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus   UniProt 20068231
S470 Phosphorylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus   UniProt 18669648, 20068231
T603 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus   UniProt 23186163
K622 Acetylation PhosphoSitePlus
K622 Sumoylation PhosphoSitePlus
K627 Acetylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus   UniProt 23186163
C714 S-Nitrosylation dbSNO 26338901
T718 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus   UniProt 18669648
K762 Sumoylation PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
K776 Ubiquitination PhosphoSitePlus
R813 Methylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
S893 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   RLIMS-P 23746640
S930 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S955 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1000 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S98 Phosphorylation HPRD 17924679, 19691289, 20068231, ...19007248
S120 Phosphorylation HPRD 18669648
S126 Phosphorylation HPRD 18669648, 19691289, 20068231
S128 Phosphorylation HPRD 18669648, 20068231
S131 Phosphorylation HPRD 18669648, 19691289, 20068231
S210 Phosphorylation HPRD 19007248, 20068231, 19691289
S291 Phosphorylation HPRD 18669648, 16565220
S309 Phosphorylation HPRD 18669648
T312 Phosphorylation HPRD 18669648
T394 Phosphorylation HPRD 20068231, 18452278
S400 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S407 Phosphorylation HPRD 18669648
T412 Phosphorylation HPRD 18669648
S437 Phosphorylation HPRD 20068231
S470 Phosphorylation HPRD 20068231
S556 Phosphorylation HPRD 20068231
S561 Phosphorylation HPRD 20068231
S591 Phosphorylation HPRD 18669648, 20068231
T603 Phosphorylation HPRD 18669648
T708 Phosphorylation HPRD 19691289, 20068231
S710 Phosphorylation HPRD 19691289
S724 Phosphorylation HPRD 20068231
S726 Phosphorylation HPRD 18669648
S756 Phosphorylation HPRD 18669648, 20068231
S936 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 C24 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S81 L81 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R106 H106 Biomuta DOID:1909 / melanoma [ cosmic ]
R106 C106 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc ]
S126 Y126 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y135 H135 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S210 Y210 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K323 N323 Biomuta DOID:363 / uterine cancer [ tcga ]
S407 Y407 Biomuta DOID:3070 / malignant glioma [ cosmic, tcga ]
C714 F714 Biomuta DOID:3953 / adrenal gland cancer [ tcga ]
S833 F833 Biomuta DOID:1909 / melanoma [ tcga ]
S977 R977 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]