iPTMnet Report Q69YH5 CDCA2

Protein Information

UniProt AC / UniProt ID	Q69YH5 / CDCA2_HUMAN
Protein Name	Cell division cycle-associated protein 2
Gene Name	Name: CDCA2
Organism	Homo sapiens (Human)

PRO ID	PR:Q69YH5 DAG View
PRO Name	cell division cycle-associated protein 2 (human)
Definition	A cell division cycle-associated protein 2 that is encoded in the genome of human.
Short Label	hCDCA2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q69YH5 (CDCA2) as Substrate

Expanded View

Site	PTM Type	PTM Enzyme	Score	Source	PMID
K6	Methylation		score1	PhosphoSitePlus
K13	Methylation		score1	PhosphoSitePlus
S24	Phosphorylation		score1	PhosphoSitePlus
T47	Phosphorylation		score1	PhosphoSitePlus
K52	Methylation		score1	PhosphoSitePlus
S53	Phosphorylation		score1	PhosphoSitePlus
T59	Phosphorylation		score1	PhosphoSitePlus
T68	Phosphorylation		score1	PhosphoSitePlus
S76	Phosphorylation		score1	PhosphoSitePlus
K79	Ubiquitination		score1	PhosphoSitePlus
S81	Phosphorylation		score1	PhosphoSitePlus
S91	Phosphorylation		score1	PhosphoSitePlus
R96	Methylation		score1	PhosphoSitePlus
S98	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163, 20068231
T101	Phosphorylation		score1	PhosphoSitePlus
R106	Methylation		score1	PhosphoSitePlus
K115	Acetylation		score1	PhosphoSitePlus
K119	Acetylation		score1	PhosphoSitePlus
K119	Methylation		score1	PhosphoSitePlus
K119	Ubiquitination		score1	PhosphoSitePlus
S120	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648, 23186163
S126	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
S128	Phosphorylation		score1	PhosphoSitePlus
S131	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
Y135	Phosphorylation		score1	PhosphoSitePlus
K182	Ubiquitination		score1	PhosphoSitePlus
S186	Phosphorylation		score1	PhosphoSitePlus
S191	Phosphorylation		score1	PhosphoSitePlus
K200	Ubiquitination		score1	PhosphoSitePlus
S205	Phosphorylation		score1	PhosphoSitePlus
S210	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
K276	Ubiquitination		score1	PhosphoSitePlus
K284	Ubiquitination		score1	PhosphoSitePlus
S286	Phosphorylation		score1	PhosphoSitePlus
S291	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
S301	Phosphorylation		score1	PhosphoSitePlus
S309	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
T312	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
K323	Ubiquitination		score1	PhosphoSitePlus
T324	Phosphorylation		score1	PhosphoSitePlus
S329	Phosphorylation		score1	PhosphoSitePlus
T394	Phosphorylation		score1	PhosphoSitePlus
S400	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163, 17081983, 18669648, ...19690332, 20068231
S407	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
T412	Phosphorylation		score4	PhosphoSitePlus RLIMS-P UniProt	18669648, 19690332, 21820363
K424	Ubiquitination		score1	PhosphoSitePlus
S437	Phosphorylation		score2	PhosphoSitePlus UniProt	20068231
S470	Phosphorylation		score1	PhosphoSitePlus
K494	Ubiquitination		score1	PhosphoSitePlus
S497	Phosphorylation		score1	PhosphoSitePlus
S507	Phosphorylation		score1	PhosphoSitePlus
S556	Phosphorylation		score1	PhosphoSitePlus
K575	Ubiquitination		score1	PhosphoSitePlus
S591	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648, 20068231
T603	Phosphorylation		score1	PhosphoSitePlus
S608	Phosphorylation		score1	PhosphoSitePlus
S614	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
K622	Acetylation		score1	PhosphoSitePlus
K622	Sumoylation		score1	PhosphoSitePlus
K627	Acetylation		score1	PhosphoSitePlus
T628	Phosphorylation		score1	PhosphoSitePlus
S710	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
C714	S-Nitrosylation		score0	dbSNO	26338901
T718	Phosphorylation		score1	PhosphoSitePlus
S724	Phosphorylation		score1	PhosphoSitePlus
S726	Phosphorylation		score1	PhosphoSitePlus
S756	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
K762	Sumoylation		score1	PhosphoSitePlus
K766	Ubiquitination		score1	PhosphoSitePlus
K776	Ubiquitination		score1	PhosphoSitePlus
R813	Methylation		score1	PhosphoSitePlus
S833	Phosphorylation		score1	PhosphoSitePlus
S874	Phosphorylation		score1	PhosphoSitePlus
S886	Phosphorylation		score1	PhosphoSitePlus
S893	Phosphorylation	Q96GD4 (AURKB)	score3	PhosphoSitePlus RLIMS-P	23746640
S930	Phosphorylation		score1	PhosphoSitePlus
S936	Phosphorylation		score2	PhosphoSitePlus UniProt	21406692, 23186163
S955	Phosphorylation		score1	PhosphoSitePlus
S960	Phosphorylation		score1	PhosphoSitePlus
S977	Phosphorylation		score2	PhosphoSitePlus UniProt	21406692, 23186163
S981	Phosphorylation		score1	PhosphoSitePlus
S1000	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163

Site	PTM Type	Score	Source	PMID
S98	Phosphorylation	score0	HPRD	17924679, 19691289, 20068231, ...19007248
S120	Phosphorylation	score0	HPRD	18669648
S126	Phosphorylation	score0	HPRD	18669648, 19691289, 20068231
S128	Phosphorylation	score0	HPRD	18669648, 20068231
S131	Phosphorylation	score0	HPRD	18669648, 19691289, 20068231
S210	Phosphorylation	score0	HPRD	19007248, 20068231, 19691289
S291	Phosphorylation	score0	HPRD	18669648, 16565220
S309	Phosphorylation	score0	HPRD	18669648
T312	Phosphorylation	score0	HPRD	18669648
T394	Phosphorylation	score0	HPRD	20068231, 18452278
S400	Phosphorylation	score0	HPRD	19651622, 18669648, 20068231, ...18452278
S407	Phosphorylation	score0	HPRD	18669648
T412	Phosphorylation	score0	HPRD	18669648
S437	Phosphorylation	score0	HPRD	20068231
S470	Phosphorylation	score0	HPRD	20068231
S556	Phosphorylation	score0	HPRD	20068231
S561	Phosphorylation	score0	HPRD	20068231
S591	Phosphorylation	score0	HPRD	18669648, 20068231
T603	Phosphorylation	score0	HPRD	18669648
T708	Phosphorylation	score0	HPRD	19691289, 20068231
S710	Phosphorylation	score0	HPRD	19691289
S724	Phosphorylation	score0	HPRD	20068231
S726	Phosphorylation	score0	HPRD	18669648
S756	Phosphorylation	score0	HPRD	18669648, 20068231
S936	Phosphorylation	score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	Disease [Sample source]
S24	C24	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
S53	L53	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S81	L81	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R96	Q96	Biomuta	DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R106	H106	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
R106	C106	Biomuta	DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ icgc ]
S126	Y126	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
Y135	H135	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S210	Y210	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
K323	N323	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S407	Y407	Biomuta	DOID:1319 / brain cancer [ cosmic, icgc ]
S470	F470	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
S470	Y470	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S507	P507	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S614	*	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ]
S726	I726	Biomuta	DOID:2394 / ovarian cancer [ cosmic ]
S833	F833	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
S936	P936	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S977	R977	Biomuta	DOID:263 / kidney cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q69YH5 (CDCA2)

Protein Information

Interactive Sequence View

Q69YH5 (CDCA2) as Substrate

PTM sites affected in variants