iPTMnet Report for Q68DX3 (FRMPD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68DX3 / FRPD2_HUMAN
Protein Name FERM and PDZ domain-containing protein 2
Gene Name Name: FRMPD2
Synonyms:PDZD5C,PDZK4,PDZK5C;
Organism Homo sapiens (Human)

PRO ID PR:Q68DX3
DAG View
PRO Name FERM and PDZ domain-containing protein 2 (human)
Definition A FERM and PDZ domain-containing protein 2 that is encoded in the genome of human.
Short Label hFRMPD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68DX3 (FRMPD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S200 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
S1227 Phosphorylation PhosphoSitePlus
S1228 Phosphorylation PhosphoSitePlus
T1270 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S283 Y283 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K336 T336 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K429 Q429 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K429 N429 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S441 N441 Biomuta DOID:4159 / skin cancer [ cosmic ]
T606 I606 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S607 N607 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S939 L939 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]