iPTMnet Report for Q68DK7 (MSL1)
Protein Information
| UniProt AC / UniProt ID | Q68DK7 / MSL1_HUMAN |
| Protein Name | Male-specific lethal 1 homolog |
| Gene Name | Name: MSL1 Synonyms:MSL1L1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q68DK7 |
| PRO Name | male-specific lethal 1 homolog (human) |
| Definition | A male-specific lethal 1 that is encoded in the genome of human. |
| Short Label | hMSL1 |
| Category | organism-gene |
Q68DK7 (MSL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K9 | Methylation | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S66 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K77 | Acetylation | score1 | PhosphoSitePlus | |||
| R79 | Methylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S205 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S205 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
| S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S252 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K272 | Acetylation | score1 | PhosphoSitePlus | |||
| K273 | Acetylation | score1 | PhosphoSitePlus | |||
| K273 | Methylation | score1 | PhosphoSitePlus | |||
| Y286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S333 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K353 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T386 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S393 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T396 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S442 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S449 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K505 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K509 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K204 | N204 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| K245 | R245 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S337 | N337 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S362 | F362 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S401 | Y401 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S401 | F401 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T409 | I409 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View