iPTMnet Report for Q68DH5 (LMBRD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68DH5 / LMBD2_HUMAN
Protein Name G-protein coupled receptor-associated protein LMBRD2
Gene Name Name: LMBRD2
Organism Homo sapiens (Human)

PRO ID PR:Q68DH5
DAG View
PRO Name G-protein coupled receptor-associated protein LMBRD2 (human)
Definition A G-protein coupled receptor-associated protein LMBRD2 that is encoded in the genome of human.
Short Label hLMBRD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68DH5 (LMBRD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T85 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y154 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
Y603 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
T611 Phosphorylation PhosphoSitePlus
T618 Phosphorylation HPRD   PhosphoSitePlus 18691976
K621 Ubiquitination PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus   UniProt 23186163
K636 Ubiquitination PhosphoSitePlus
Y637 Phosphorylation PhosphoSitePlus
S672 Phosphorylation PhosphoSitePlus
Y677 Phosphorylation PhosphoSitePlus
Y683 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T85 I85 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y154 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K296 R296 Biomuta DOID:1324 / lung cancer [ cosmic ]
S633 Y633 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y677 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S685 L685 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]