iPTMnet Report for Q68DC2 (ANKS6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68DC2 / ANKS6_HUMAN
Protein Name Ankyrin repeat and SAM domain-containing protein 6
Gene Name Name: ANKS6
Synonyms:ANKRD14,PKDR1,SAMD6;
Organism Homo sapiens (Human)

PRO ID PR:Q68DC2
DAG View
PRO Name ankyrin repeat and SAM domain-containing protein 6 (human)
Definition An ankyrin repeat and SAM domain-containing protein 6 that is encoded in the genome of human.
Short Label hANKS6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68DC2 (ANKS6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K247 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
R596 Methylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus   UniProt 23186163
S660 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S704 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus   UniProt 23186163
T736 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S660 Phosphorylation HPRD 18669648
T736 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S657 L657 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S660 N660 Biomuta DOID:1319 / brain cancer [ cosmic ]
S704 Y704 Biomuta DOID:363 / uterine cancer [ icgc ]
S724 F724 Biomuta DOID:363 / uterine cancer [ icgc ]
S742 * Biomuta DOID:10283 / prostate cancer [ cosmic ]