iPTMnet Report for Q68D10 (SPTY2D1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68D10 / SPT2_HUMAN
Protein Name Protein SPT2 homolog
Gene Name Name: SPTY2D1
Organism Homo sapiens (Human)

PRO ID PR:Q68D10
DAG View
PRO Name protein SPT2 homolog (human)
Definition A protein SPT2 that is encoded in the genome of human.
Short Label hSPTY2D1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68D10 (SPTY2D1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
K58 Methylation PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 20068231
K281 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T358 Phosphorylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus   UniProt 23186163
S480 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
K582 Acetylation PhosphoSitePlus   UniProt 19608861
S599 Phosphorylation PhosphoSitePlus   UniProt 18669648
K631 Sumoylation PhosphoSitePlus
Y636 Phosphorylation PhosphoSitePlus
Y640 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S278 Phosphorylation HPRD 20068231
S471 Phosphorylation HPRD 19691289
Y597 Phosphorylation HPRD 18669648
S599 Phosphorylation HPRD 18669648, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S41 P41 Biomuta DOID:363 / uterine cancer [ icgc ]
K58 N58 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S278 C278 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K289 R289 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T390 K390 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S544 F544 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]